Selective Lymph Node Resection for Invasive Non-small Cell Lung Cancer With the CTR of 0.5-1 and the Diameter of ≤ 2 cm: a Prospective， Single-arm, Multi-center, Phase Ⅱ Trial
The study investigated the efficacy and safety of a selective lymph node strategy (no lower mediastinal lymph node dissection for upper lobe tumors and no upper mediastinal lymph node dissection for lower lobe tumors) in patients with 0.5 \< CTR \< 1 and ≤ 2 cm in diameter cT1N0M0 infiltrating NSCLC, aiming to more accurately assess the prognosis of the selective lymph node dissection strategy for nodes with 0.5 \< CTR \< 1 and ≤ 2 cm in diameter.
• Volunteer to participate in a clinical study and be willing to follow and have the ability to complete all trial procedures;
• Age 18-80 years at time of signing informed consent (including threshold);
• ECOG score 0 or 1;
• No previous surgery for lung cancer;
• Intraoperative or postoperative pathologically confirmed non-small cell lung cancer;
• Single pulmonary nodule with mixed ground glass on CT, or multiple pulmonary nodules but the main lesion is the above nodules;
• The proportion of solid components of the nodule is between 0.5 and 1, and the total size of the nodule is less than or equal to 2 cm;
• Patients with clinical stage T1N0M0 surgically resectable;
• Primary treatment without radiotherapy or chemotherapy.